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For testosterone replacement therapy (TRT), clinicians can use several different forms of testosterone. The choice depends on preference, cost, absorption, and how stable you want testosterone levels to be. Common options include: - Injectable testosterone esters - Testosterone cypionate (Depo-Testosterone) - Testosterone enanthate (Delatestryl) - Dosing is usually every 1–4 weeks (often every 1–2 weeks) - Long-acting injectable - Testosterone undecanoate (Aveed, Nebido) - Dosed every about 10–14 weeks after initial doses - Transdermal options - Gels: AndroGel, Testim, Fortesta, Vogelxo (applied daily to skin) - Patches: Androderm (applied nightly) - Buccal/tablet option - Striant (buccal testosterone) — placed on the gum, typically twice daily - Nasal testosterone - Natesto (nasal gel) — used a few times per day - Oral testosterone - Testosterone undecanoate formulations (e.g., Jatenzo in the US; others used in some countries) - Taken with meals; historically more variable absorption and different safety considerations - Subcutaneous implants - Testosterone pellets implanted under the skin (typically every 3–6 months) Notes - The best form depends on you: how often you want to dose, skin sensitivity, risk of transfer to others (gels/patches can transfer if you’re in close contact), and cost/availability. - TRT should be guided by a clinician after confirming testosterone deficiency with labs and symptoms. - Monitoring typically includes testosterone levels (to hit mid-normal range), hematocrit, PSA, lipid panel, and liver tests as indicated, plus checking for side effects. If you tell me your location and whether you prefer injections, gels, or a non-daily option, I can outline what’s most commonly used there and typical pros/cons for that choice.
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