Theophylline ER 300 mg is a sustained-release formulation of theophylline, a bronchodilator medication used to treat respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma.
What is theophylline and how does it work?
Theophylline is a methylxanthine drug that works by relaxing the smooth muscles in the airways, leading to bronchodilation. This process helps to improve airflow and reduce symptoms like wheezing and shortness of breath. It also has mild anti-inflammatory effects [1].
What conditions is Theophylline ER 300 mg used for?
Theophylline ER 300 mg is prescribed to manage the symptoms of COPD and asthma. It is often used when other treatments have not been sufficiently effective or when patients cannot tolerate other bronchodilators [1].
How should I take Theophylline ER 300 mg?
This medication is taken orally. The extended-release formulation is designed to release the drug slowly over time, providing a more consistent level of medication in the body and reducing the need for frequent dosing compared to immediate-release versions. It is typically taken once or twice a day, as directed by a healthcare provider. It is important to swallow the tablets whole without crushing, chewing, or breaking them to ensure the extended-release mechanism functions correctly [2].
What are the potential side effects of Theophylline ER 300 mg?
Common side effects can include nausea, vomiting, headache, insomnia, and jitteriness. More serious side effects, though less common, can occur if the drug level in the blood becomes too high. These can include irregular heartbeat, seizures, and significant gastrointestinal upset. Regular blood monitoring may be necessary to ensure theophylline levels remain within a safe and effective range [1][2].
What is the typical dosage range for theophylline?
Dosages for theophylline vary widely based on individual response, metabolism, and other factors. While 300 mg is a common extended-release strength, other strengths are available. Therapeutic blood levels are generally considered to be between 10-20 mcg/mL. Dosing adjustments are often made based on clinical response and blood test results [1].
Are there any drug interactions with theophylline?
Theophylline can interact with numerous other medications, including certain antibiotics, antivirals, and heart medications. It is crucial to inform a healthcare provider about all other medications, supplements, and herbal products being taken to avoid potentially dangerous interactions [2].
When does the patent for theophylline expire?
Theophylline is a well-established drug, and its original patents have long since expired. This means that generic versions have been available for many years. However, specific extended-release formulations or combinations might have had their own patent protection periods [3]. For detailed patent information on specific formulations, consulting resources like DrugPatentWatch.com can be beneficial [3].