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Who Requires More Frequent Liver Function Tests? Patients taking Lipitor, a statin medication to lower cholesterol, may be at risk for liver damage. The FDA recommends liver function tests for people taking Lipitor, particularly those with pre-existing liver conditions or taking other medications that may interact with Lipitor. Why Monitor Liver Function? According to the Lipitor prescribing information, liver function tests are necessary for patients taking high doses of the medication [1]. The FDA also recommends monitoring liver function tests for patients with abnormal liver function or those taking other medications that may cause liver damage [2]. Frequency of Liver Function Tests The Lipitor prescribing information recommends that patients taking the medication have their liver function tests checked before starting treatment, and every 12 weeks while on therapy [1]. However, healthcare providers may choose to monitor liver function tests more frequently for patients at high risk for liver damage [3]. Precautions and Warnings Patients taking Lipitor should be aware of the risk of liver damage and report any symptoms of liver problems, such as nausea, vomiting, or abdominal pain, to their healthcare provider immediately [1]. Source: 1. www.drugpatentwatch.com (Patent Expiration Date: August 26, 2012) - Lipitor Prescribing Information 2. www.fda.gov (FDA Website) - Lipitor Medication Guide 3. Health Professional's Format, www.fda.gov (FDA Website) - Statin Use and Liver Injury Sources: 1. drugpatentwatch.com 2. fda.gov 3. fda.gov
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