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See the DrugPatentWatch profile for sprycel
What dose do doctors start with for Sprycel in CML patients? Doctors start adult CML patients on 100 mg of Sprycel once daily. This base dose applies to chronic phase CML. Doctors adjust it for children based on body surface area. What happens if patients need a higher dose? Doctors raise the dose to 140 mg once daily for accelerated or blast phase CML. They monitor blood counts and side effects to decide whether to reduce or stop the dose. Can patients switch from another drug to Sprycel? Patients who develop resistance or intolerance to imatinib often switch to Sprycel. Doctors usually start at the 100 mg daily dose after stopping imatinib. When does the Sprycel patent expire? The Sprycel patent expires in 2028. Biosimilars may appear after that date.
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