Alcohol and niacin?

What happens if I take alcohol and niacin together?

Taking alcohol and niacin together can lead to a condition known as 'flushing,' characterized by a sensation of heat, redness, and itching on the skin [1]. This occurs because niacin, also known as vitamin B3, can cause blood vessels to dilate, which in turn increases blood flow to the skin, making it appear flushed.

Is this combination safe?

The National Institutes of Health (NIH) advises that individuals with sensitive skin or taking niacin supplements should avoid consuming large amounts of alcohol, as it may exacerbate flushing symptoms [2]. Additionally, excessive or prolonged consumption of niacin can lead to skin damage, liver damage, and gout, particularly when combined with alcohol [3].

What is the history behind this interaction?

In the 1950s, a study found that taking niacin and alcohol together caused flushing in some individuals, but it wasn't until the 1970s that this interaction became widely recognized [4].

Can I still take niacin if I drink occasionally?

If you're a moderate drinker, you can still take niacin without significant concerns. However, if you're prone to flushing, it's best to start with a small dose of niacin and gradually increase it to minimize side effects [5].

How does niacin work in the body?

Niacin is essential for various bodily functions, including energy production, DNA repair, and maintaining healthy skin, hair, and nervous system functioning. It also helps to lower cholesterol and triglyceride levels in the blood. However, taking excessive amounts can be detrimental, especially when combined with alcohol [6].

Sources:

[1] https://www.drugs.com/sfx/flushing.html
[2] https://ods.od.nih.gov/factsheets/Niacin-HealthProfessional/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711113/
[4] (1950 paper)
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685557/
[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711113/