Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. While it is generally safe to take, there are some supplements that may interact negatively with it.

According to Drug Patent Watch [1], there are no known drug interactions with Lipitor. However, it is important to note that this does not mean that there are no potential interactions with supplements.

SingleCare [2] notes that there are some supplements that may interact negatively with Lipitor. For example, taking large amounts of niacin (vitamin B3) may increase the risk of muscle damage when taken with statins such as Lipitor. Additionally, taking supplements containing red yeast rice may increase the risk of muscle damage and liver toxicity when taken with statins.

ConsumerLab [3] also notes that there are some supplements that should be avoided when taking statins such as Lipitor. These include supplements containing St. John's Wort, which may decrease the effectiveness of the medication, and supplements containing grapefruit juice, which may increase the risk of side effects.

In summary, while there are no known drug interactions with Lipitor, there are some supplements that may interact negatively with the medication. These include supplements containing large amounts of niacin, red yeast rice, St. John's Wort, and grapefruit juice. If you are taking Lipitor and are considering taking any supplements, it is important to speak with your healthcare provider to ensure that they are safe to take together.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-interactions/
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/