What's the typical onset time for advil headache relief?

Typically, Advil (ibuprofen) starts helping a headache about 30–60 minutes after you take a dose. Peak relief is usually in about 1–2 hours, and the effect lasts around 4–6 hours.

Tips:
- Common OTC adult dose is 200–400 mg every 4–6 hours as needed (do not exceed 1200 mg in 24 hours without a clinician’s advice).
- Take with water; taking with food may help if you get stomach upset.
- Don’t use if you have kidney disease, ulcers, certain heart conditions, or if you’re in the third trimester of pregnancy without medical supervision.
- If headaches persist beyond a couple of days or are worsening, consult a healthcare provider. If you have any questions about interactions with other meds (e.g., other NSAIDs, anticoagulants), ask a clinician.