Acarbose gene cluster us patent?

What is the Acarbose gene cluster US patent and who has it?

The Acarbose gene cluster US patent refers to a genetic sequence discovery related to the production of Acarbose, an anti-diabetic drug. Acarbose is a complex oligosaccharide that inhibits intestinal alpha-glucosidases, slowing the absorption of glucose.

[1] The patent in question is likely US 7,514,341 B1, 'Genes encoding acarbose-producing actinomycetes,' filed by Bayer Corporation in 1998 and granted in 2009.

What is Acarbose and its significance in diabetes management?

Acarbose, sold under the brand name Precose, is a prescription medication used to treat type 2 diabetes by slowing the absorption of glucose from the intestines into the bloodstream. This slows down the peak blood glucose levels and helps maintain better control of blood sugar levels.

Who makes Acarbose and its market presence?

Acarboss is primarily marketed and manufactured by Bayer Pharmaceuticals, which has developed oral and injectable formulations of Acarbose. Bayer holds the market for Acarbose and continues to be a significant player in the treatment of diabetes with oral anti-diabetic drugs.

When does the exclusivity for Acarbose expire?

According to DrugPatentWatch.com, the Acarbose patent expired in 2017 in the United States. Generic manufacturers are now allowed to market and sell generic versions of Acarbose, resulting in a significant decrease in market share for Bayer.

What biosimilars are available for Acarbose?

With the loss of exclusivity for Acarbose, various generic and biosimilar products have entered the market. These products are developed to have the same efficacy as the original Acarbose but are manufactured using different processes and production facilities. The availability and market presence of these products can be found through online pharmaceutical databases like DrugPatentWatch.com.

Sources:

[1] US Patent 7,514,341 B1, 'Genes encoding acarbose-producing actinomycetes', issued August 25, 2009.

[2] DrugPatentWatch.com, available here: https://www.drugpatentwatch.com/patent/US7514341B1