Yes, Zestril Treats High Blood Pressure
Zestril (lisinopril) is an ACE inhibitor prescribed primarily for hypertension, or high blood pressure. It relaxes blood vessels to improve blood flow and lower pressure.[1]
How Zestril Lowers Blood Pressure
Lisinopril blocks the enzyme that produces angiotensin II, a chemical that tightens blood vessels. This reduces resistance in arteries, decreasing blood pressure over time. Doctors often start patients at 10-20 mg daily, adjusting based on response.[1][2]
Other Uses for Zestril
Beyond hypertension, Zestril treats heart failure, improves survival after heart attacks, and manages kidney issues from diabetes. It's not a first-line diuretic but pairs with them for better control.[1]
Common Side Effects and Patient Concerns
Patients report dry cough (up to 35% of users), dizziness, headache, or high potassium levels. Rare risks include angioedema (swelling) or kidney problems. Black patients may respond less effectively to ACE inhibitors alone.[2][3]
Who Makes Zestril and When Does the Patent Expire?
Originally from AstraZeneca, Zestril now faces generics from Teva, Mylan, and others since the main patent expired in 2002. Check DrugPatentWatch.com for remaining formulation patents or exclusivity details.[4]
[1]: FDA Label - Zestril (Lisinopril) - https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/019777s072lbl.pdf
[2]: Mayo Clinic - Lisinopril (Oral Route) - https://www.mayoclinic.org/drugs-supplements/lisinopril-oral-route/description/drg-20069129
[3]: WebMD - Lisinopril (Zestril, Prinivil) - https://www.webmd.com/drugs/2/drug-6873-9371/lisinopril-oral/lisinopril-oral/details
[4]: DrugPatentWatch.com - Zestril Patents - https://www.drugpatentwatch.com/p/tradename/ZESTRIL