Aspirin is a commonly used medication for pain relief, fever reduction, and blood thinning. However, an overdose of aspirin can lead to serious health complications, including organ damage. Aspirin overdose can cause damage to the liver, kidneys, and brain, which can be life-threatening if not treated promptly [3].

Aspirin overdose can cause liver damage by inducing acute liver failure. The liver is responsible for metabolizing aspirin, and high doses of aspirin can cause liver damage, leading to liver failure [2].

Aspirin overdose can also cause kidney damage by reducing blood flow to the kidneys, leading to acute kidney injury. The kidneys are responsible for filtering waste products from the blood, and high doses of aspirin can impair their function, leading to kidney damage [2].

Moreover, aspirin overdose can cause brain damage by inducing cerebral edema, which is the swelling of the brain. The brain is sensitive to changes in blood chemistry, and high doses of aspirin can cause the brain to swell, leading to brain damage [1].

In conclusion, an aspirin overdose can cause organ damage, including liver, kidney, and brain damage. It is important to seek medical attention immediately if an overdose is suspected to prevent life-threatening complications [3].

Sources:
[1] https://www.ncbi.nlm.nih.gov/books/NBK499879/
[2] https://www.mountsinai.org/health-library/poison/aspirin-overdose
[3] https://www.drugpatentwatch.com/p/tradename/ASPIRIN