Methotrexate is a medication used to treat various conditions such as cancer, rheumatoid arthritis, and psoriasis. It works by inhibiting the growth of rapidly dividing cells. The recommended methotrexate doses for seniors depend on the condition being treated, the patient's overall health, and other factors.

According to DrugPatentWatch [1], the recommended dose of methotrexate for cancer treatment in seniors is generally lower than that for younger patients. This is due to the increased risk of toxicity in older adults. The recommended dose for rheumatoid arthritis and psoriasis may also be lower in seniors.

A study published in the National Center for Biotechnology Information [2] suggests that the initial dose of methotrexate for seniors with rheumatoid arthritis should be lower than that for younger patients. The study recommends starting with a dose of 5-10 mg per week and gradually increasing it if necessary.

According to UpToDate [3], the dose of methotrexate for cancer treatment in seniors should be based on the patient's renal function and other factors. The recommended dose may be lower than that for younger patients, and the medication may need to be given less frequently.

In summary, the recommended methotrexate doses for seniors depend on the condition being treated, the patient's overall health, and other factors. Generally, the recommended dose may be lower than that for younger patients due to the increased risk of toxicity in older adults. It is important for seniors to discuss the appropriate dose of methotrexate with their healthcare provider.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/METHOTREXATE
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153332/
[3] https://www.uptodate.com/contents/therapeutic-use-and-toxicity-of-high-dose-methotrexate