See the DrugPatentWatch profile for Humira
What are the common side effects of Humira (adalimumab)?
Humira (adalimumab) can cause side effects related to immune system changes and injection-site reactions. Commonly reported effects include:
- Injection-site reactions (such as redness, itching, pain, swelling, bruising, or rash) [1]
- Upper respiratory infections (like the common cold or sinus symptoms) [1]
- Headache [1]
- Nausea [1]
- Rash [1]
How serious are Humira side effects, and when should you seek care?
Some reactions may need urgent medical attention, especially those suggesting an infection or a severe allergic reaction. Get prompt medical care if you develop:
- Signs of a serious infection (high fever, chills, severe weakness, shortness of breath, worsening cough, or pain that is getting worse)
- Symptoms of tuberculosis (persistent cough, night sweats, weight loss) since anti-TNF medicines can reactivate TB
- Signs of a serious allergic reaction (swelling of the face/lips, trouble breathing, widespread hives)
- Severe skin reactions or unusual bruising/bleeding
Can Humira cause infections or infections that feel “more frequent”?
Yes. Because Humira suppresses part of the immune response, people may be more likely to get infections. Common ones reported include upper respiratory infections, but serious infections can also occur [1].
Does Humira cause long-term side effects?
Some risks with long-term use can include liver problems, blood cell count changes, and certain malignancies, but these are not usually described as the most “common” side effects. Patients are typically monitored and advised to report new symptoms promptly [1].
Who is more likely to have side effects?
Risk can be higher in people with:
- Existing infections or frequent infections
- History of tuberculosis exposure
- Certain chronic conditions (your clinician may screen and monitor more closely)
- Use with other medicines that also affect the immune system
What should you tell your doctor if you’re getting side effects?
Report any injection-site reactions that are severe or worsening, any fever or infection symptoms, and any new rash or breathing/swelling symptoms. Your clinician may decide whether to adjust treatment or pause dosing based on what’s happening.
Sources
[1] https://www.rxlist.com/humira-side-effects-drug-center.htm