Acyclovir is an antiviral medication that is used to treat infections caused by herpes viruses, including genital herpes, cold sores, shingles, and chickenpox. There is no evidence to suggest that acyclovir weakens the immune response. In fact, the drug works by inhibiting the replication of the virus, which allows the immune system to better fight off the infection [2].

Acyclovir is a nucleoside analogue that works by inhibiting viral DNA synthesis. It is not known to have any direct effect on the immune system. However, it is important to note that while acyclovir can help to reduce the severity and duration of herpes virus infections, it does not cure them. The immune system is still responsible for clearing the virus from the body [3].

According to Drug Patent Watch, acyclovir was first approved by the FDA in 1985 and is available in a variety of formulations, including oral tablets, capsules, and suspensions, as well as topical creams and ointments [1].

In summary, acyclovir is an antiviral medication that does not weaken the immune response. It works by inhibiting viral DNA synthesis and allows the immune system to better fight off the infection. However, it is important to note that acyclovir does not cure herpes virus infections, and the immune system is still responsible for clearing the virus from the body.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ACYCLOVIR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414608/
[3] https://rxoutreach.org/monograph/acyclovir/