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See the DrugPatentWatch profile for aristada
Aristada is the brand name for aripiprazole lauroxil, a long‑acting injectable antipsychotic made by Alkermes (often used in schizophrenia). It is a prodrug that slowly converts to aripiprazole in the body and is given by intramuscular injection. Key points - Indication: Treatment of schizophrenia in adults. - How it works: Long-acting injectable that provides gradual release of aripiprazole after injection. - Dosing and schedule: - Available in several strengths (commonly 441 mg, 662 mg, and 882 mg per injection). - Given by deep IM injection into the deltoid or gluteal muscle. - Administered every 4 to 6 weeks (interval depends on dose and patient factors; some doses may be used every 6 weeks). - Initiation may require bridging with oral aripiprazole for about 21 days after the first Aristada injection unless you are using Aristada Initio, which is an initiation option designed to avoid bridging. - Administration notes: - Administer only by a healthcare professional. - Store according to label directions (usually refrigerated until use; allow to reach room temp before injection; do not shake the suspension). - Common side effects: injection-site reactions, akathisia (inner restlessness), weight changes, sedation, nausea, dizziness, and headache. As with other antipsychotics, there is a risk of metabolic effects, extrapyramidal symptoms, and other serious adverse effects. - Important safety info: - Elderly patients with dementia-related psychosis have an increased risk of death with antipsychotics. - Can interact with other medicines that affect liver enzymes (notably CYP3A4 and CYP2D6), CNS depressants, and other antipsychotics. - Pregnancy, breastfeeding, and use in children/adolescents require careful medical advice. - Contraindications: Known hypersensitivity to aripiprazole lauroxil or any components of the injection. If you want, I can summarize the exact dosing options (which strength to use and the corresponding 4‑ or 6‑week interval) or pull up the official labeling details. Do you want a patient-friendly dosing guide or more technical dosing information?
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