Dose of vancomycin?

Dosing vancomycin isn’t one-size-fits-all. It depends on route, infection site, weight, age, and kidney function. Here are the common adult guidelines, with a request for your specifics to tailor it:

- IV vancomycin (adult, serious infection or MRSA suspected)
- Typical dose: 15–20 mg/kg every 8–12 hours
- Frequency adjusted by kidney function:
- CrCl > 50 mL/min: every 8–12 hours
- CrCl 20–50 mL/min: roughly every 24 hours
- CrCl < 20 mL/min: every 48–72 hours
- Some authors use a loading dose (about 25–30 mg/kg) in severe infections to rapidly reach target levels.
- Trough goal (for many serious infections): 15–20 mcg/mL
- Important: use actual body weight (and consider adjusted body weight if very obese)

- Oral vancomycin (for C. difficile)
- 125 mg PO QID for mild-to-moderate disease
- 500 mg PO QID for severe disease
- Typical duration: about 10 days (adjust as needed)

- Pediatric dosing (brief)
- Usually weight-based, around 10–15 mg/kg per dose IV every 6–8 hours, adjusted for renal function

- Important safety notes
- Monitor renal function and drug levels if possible
- Infuse IV vancomycin slowly (at least 60 minutes) to reduce red man syndrome
- Dose must be individualized; a clinician may adjust based on labs and response

If you can share:
- route (IV or oral)
- patient weight and renal function (CrCl or eGFR)
- infection type or site
- age (adult vs child)

I can give a more precise dosing range.