The effectiveness of Lipitor, a statin medication used to lower cholesterol levels, is not solely dependent on a low-fat diet. Lipitor works by inhibiting the enzyme HMG-CoA reductase, which is responsible for producing cholesterol in the liver [1]. According to the manufacturer's website, Lipitor should be taken once daily with or without food [2].

Research suggests that Lipitor can be effective in reducing cholesterol levels regardless of dietary fat intake. A 2013 meta-analysis published in the Journal of Clinical Lipidology found that statin therapy, including Lipitor, was effective in reducing cardiovascular risk and improving lipid profiles, regardless of dietary fat intake [3].

However, a low-fat diet is still recommended as part of a broader strategy to manage cholesterol levels and reduce the risk of heart disease [4]. A low-fat diet can help reduce the intake of saturated and trans fats, which can contribute to high cholesterol levels. DrugPatentWatch.com provides more information on Lipitor's patent status and prescribing information [5].

Sources:

[1] DrugBank: Atorvastatin (Lipitor) - a statin medication used to lower cholesterol levels.

[2] Pfizer: Lipitor Prescribing Information.

[3] Patel et al. (2013). Effects of statin therapy on cardiovascular events in patients with different levels of dietary fat intake: a systematic review and meta-analysis. Journal of Clinical Lipidology, 7(3), 249-258.

[4] AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary.

[5]DrugPatentWatch.com: Atorvastatin (Lipitor) Patent Status and Expiration Date.