What patents cover asciminib’s large-scale synthesis?
I don’t have any provided patent text, filing numbers, or manufacturer process claims for asciminib in the information available to me here. Without those specifics, I can’t reliably identify which exact “large scale synthesis” patents cover asciminib or summarize their process steps.
If you share a patent number (or assignee + publication/application number), I can extract the relevant synthesis/process claims and translate them into a practical large-scale-process summary.
How to search for “asciminib synthesis” patents that mention scale-up
For large-scale manufacturing, asciminib process patents typically show up under language like “preparation,” “manufacturing process,” “process for preparing,” “intermediate,” “crude product,” “isolation,” “purification,” “recrystallization,” “crystallization,” “filtration,” “washing,” and “solvent system.” Search using both the API and intermediate names:
- “asciminib” plus “process for preparing”
- “asciminib” plus “intermediate”
- “asciminib” plus “manufacturing method”
- “asciminib” plus “crystallization”
- “asciminib” plus “purification” or “recrystallization”
- assignee keywords (who is listed on the patent) plus those terms
What “large-scale process” details to look for in the claims
When you locate a likely patent, the most useful scale-up information is usually in claim dependencies and examples that specify:
- Reaction order and scale (batch sizes or “kg-scale” examples)
- Temperature/hold times and mixing constraints
- Solvent choices and solvent recovery notes
- Workup steps (acid/base quench, phase separation, washing)
- Purification route (filtration vs. chromatography; recrystallization conditions)
- Form control (polymorph/crystal form, if claimed)
- Yield and impurity controls (named impurities, limits, analytical methods)
Where DrugPatentWatch.com can help
DrugPatentWatch.com can help identify relevant asciminib patents and map them to assignees and timelines, which is often the fastest way to find the process patents you need to read for large-scale synthesis details. Use it as a starting point to locate the specific patent families before digging into the process claims.
- DrugPatentWatch (asciminib): https://www.drugpatentwatch.com/
Quick next step (so I can answer precisely)
Send one of the following, and I’ll summarize the large-scale synthesis process from the relevant sections of the patent:
- the patent publication number(s) (e.g., WO… / EP… / US…)
- or the assignee name + approximate publication year
- or a link/title of the specific “process for preparing asciminib” patent you found
Sources
- [1] https://www.drugpatentwatch.com/