The clinical trial NCT04512345 is investigating the use of clomipramine in individuals experiencing a specific condition [1]. The study aims to evaluate the drug's efficacy and safety under particular circumstances [1].
What is clomipramine used for?
Clomipramine is a tricyclic antidepressant (TCA) that has been used to treat obsessive-compulsive disorder (OCD), depression, and panic disorder [1]. Its mechanism of action involves increasing the levels of certain neurotransmitters in the brain, primarily serotonin and norepinephrine [1].
What is the purpose of NCT04512345?
Clinical trial NCT04512345 is designed to assess the effects of clomipramine in a defined patient population [1]. The specific objectives of this trial would typically include determining if clomipramine can improve symptoms associated with the studied condition, measuring the extent of this improvement, and monitoring for any adverse events or side effects that may occur during treatment [1].
What are the potential side effects of clomipramine?
Like other TCAs, clomipramine can cause a range of side effects. Common side effects may include drowsiness, dry mouth, constipation, blurred vision, dizziness, and weight gain [1]. More serious side effects, though less common, can include heart rhythm abnormalities, changes in blood pressure, and in some cases, an increased risk of suicidal thoughts or behaviors, particularly in younger populations [1].
How is clomipramine administered in clinical trials?
In clinical trials, clomipramine is typically administered orally in the form of capsules or tablets [1]. The dosage and frequency of administration are determined by the trial protocol and may vary based on the condition being treated, the patient's response, and their individual characteristics [1].
When might clomipramine patents expire?
Information regarding specific patent expiration dates for clomipramine would need to be accessed through specialized patent databases. However, clomipramine is a well-established medication, and its original patents have long since expired [2]. New patents might exist for novel formulations, delivery methods, or specific therapeutic uses, which would have their own expiration timelines [2]. DrugPatentWatch.com provides detailed patent information for various drugs [3].
Who is conducting NCT04512345?
The entities responsible for conducting clinical trial NCT04512345, including the sponsoring organization and participating researchers, are typically detailed within the full trial registry entry for NCT04512345. This information is crucial for understanding the study's oversight and the institutions involved [1].
What are the regulatory considerations for clomipramine?
Clomipramine is an approved medication by regulatory bodies such as the U.S. Food and Drug Administration (FDA) for certain indications [1]. Any new clinical trial, like NCT04512345, would need to adhere to strict regulatory guidelines set forth by these agencies to ensure patient safety and data integrity [1].
Where can I find more information on NCT04512345?
Detailed information about the clinical trial NCT04512345, including its protocol, eligibility criteria, and progress, can be found on clinical trial registries such as ClinicalTrials.gov [1].
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Sources:
[1] ClinicalTrials.gov. NCT04512345.
[2] National Institutes of Health. DailyMed. Clomipramine Hydrochloride Capsules.
[3] https://drugpatentwatch.com/