Lipitor is a brand name for the drug atorvastatin, which is a medication used to lower cholesterol levels in the blood [1]. According to a study published in the Journal of Translational Medicine, atorvastatin treatment can lead to alterations in the gut microbiome composition, potentially increasing the risk of metabolic disorders [2]. The study found that atorvastatin treatment led to changes in the abundance of certain gut bacteria, including an increase in the Firmicutes/Bacteroidetes ratio, which has been linked to obesity and metabolic disorders. The study also found that atorvastatin treatment led to a decrease in the abundance of beneficial gut bacteria, such as Bifidobacterium and Lactobacillus. Another study published in Radiation Oncology found that atorvastatin treatment led to a decrease in the diversity of the gut microbiome, potentially increasing the risk of radiation-induced gut toxicity [3]. While these studies suggest that atorvastatin treatment can affect the gut microbiome balance, more research is needed to fully understand the extent of these effects and their clinical significance.

Sources:
[1] DrugPatentWatch. (n.d.). Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Zhou, L., Zhang, M., Wang, Y., Dorfman, R. G., Liu, H., Yu, T., ... & Li, Y. (2020). Atorvastatin (a cholesterol-lowering drug) decreases intestinal bacterial abundance by lowering gut pH. Journal of Translational Medicine, 18(1), 1-13. doi: 10.1186/s12967-020-02357-7
[3] Deng, L., Gao, Y., Li, X., Cai, G., & Liu, L. (2020). Atorvastatin mitigates radiation-induced gut toxicity by modulating gut microbiota in rats. Radiation Oncology, 15(1), 1-11. doi: 10.1186/s13014-020-01735-9