Us patent application biosynthetic heparin?

Do you want a US patent-focused overview of biosynthetic heparin (i.e., US patent publications and/or granted patents about producing heparin or heparan sulfate-like anticoagulants in a biosynthetic way)?

I can help with:
- A landscape overview (who is filing, what kinds of claims they make, typical claim categories).
- A list of US patent publications and/or granted patents related to biosynthetic or chemoenzymatic production of heparin/heparan sulfate.
- Status notes (pending, granted, expired) and assignees.
- How to search effectively (databases, search terms, and how to read the claims).

Before I dive in, a couple of clarifying questions:
- Do you want US patent applications only, or both US published applications and granted US patents?
- Are you interested in all biosynthetic approaches (recombinant production of heparosan, chemoenzymatic sulfation, enzymatic modification of glycosaminoglycans, etc.), or a narrower focus (e.g., chemoenzymatic synthesis of heparin versus full recombinant biosynthesis in microbes)?
- Do you want recent filings only, or a broader history (past 5–10+ years)?

If you’d like, I can give you a plan to search now and then summarize results you pull back. For example, a starting search could use terms like:
- biosynthetic heparin
- recombinant heparin
- chemoenzymatic synthesis of heparin
- heparosan sulfotransferase
- engineered heparan sulfate
- biosynthetic production of heparin in microbes

Then filter to US publications (US 20xx/-year) and sort by status (granted vs. application). I can then help you parse the claims and identify likely key players (assignees) and summarize the scope.

Would you like me to proceed with a targeted US-patent search plan and provide a first-draft landscape once you confirm your preferences? If you have a specific assignee or timeframe in mind, tell me and I’ll tailor the approach.