Lurbinectedin is a medication used for the treatment of cancer. The drug works by inhibiting the activity of an enzyme called RNA polymerase II, which is responsible for the transcription of DNA into RNA. According to the sources provided, there are several potential side effects associated with the use of lurbinectedin.

The most common side effects of lurbinectedin include fatigue, nausea, vomiting, decreased appetite, constipation, and diarrhea. Other potential side effects include anemia, low white blood cell count, low platelet count, fever, chills, headache, muscle pain, joint pain, peripheral edema, and abnormal liver function tests. Some patients may also experience allergic reactions, including rash, itching, and difficulty breathing.

In rare cases, lurbinectedin can cause serious side effects, such as severe infections, bleeding, and heart problems. Patients who experience symptoms such as chest pain, shortness of breath, or fainting should seek medical attention immediately.

It is important to note that not all patients will experience these side effects, and some may experience different side effects than those listed here. Patients should discuss the potential risks and benefits of lurbinectedin with their healthcare provider before starting treatment.

Sources:
[1] Drug Patent Watch. Lurbinectedin. https://www.drugpatentwatch.com/p/tradename/LURBINECTEDIN
[2] Mayo Clinic. Lurbinectedin (Intravenous Route): Side Effects. https://www.mayoclinic.org/drugs-supplements/lurbinectedin-intravenous-route/side-effects/drg-20490804?p=1
[3] Zepzelca. Zepzelca Side Effects. https://www.zepzelca.com/zepzelca-side-effects/