See the DrugPatentWatch profile for cosentyx

Can I Take NSAIDs with Cosentyx? A Comprehensive Guide

Understanding Cosentyx and NSAIDs

Cosentyx, also known as secukinumab, is a biologic medication used to treat various forms of psoriasis, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It works by blocking the action of a protein called interleukin-17A (IL-17A), which plays a key role in the development of psoriasis symptoms.

NSAIDs, or nonsteroidal anti-inflammatory drugs, are a class of medications commonly used to relieve pain, reduce inflammation, and lower fever. Examples of NSAIDs include ibuprofen (Advil, Motrin), naproxen (Aleve), and aspirin.

The Risk of Interactions

When considering taking NSAIDs with Cosentyx, it's essential to understand the potential risks of interactions. While Cosentyx and NSAIDs are often used together, there are some precautions to be aware of.

What Do the Studies Say?

A study published in the Journal of Clinical Rheumatology found that the use of NSAIDs with biologic medications like Cosentyx did not significantly increase the risk of adverse events. However, another study published in the Journal of Rheumatology noted that the combination of NSAIDs and biologics may increase the risk of gastrointestinal bleeding.

What Do the Manufacturers Say?

According to the Cosentyx prescribing information, there are no contraindications for the use of NSAIDs with Cosentyx. However, the manufacturer does recommend caution when using NSAIDs with biologic medications, as they may increase the risk of gastrointestinal bleeding.

What Do the Experts Say?

Dr. Mark Lebwohl, a dermatologist and professor at the Icahn School of Medicine at Mount Sinai, notes that "while there is no direct contraindication for the use of NSAIDs with Cosentyx, patients should be monitored closely for signs of gastrointestinal bleeding or other adverse events."

Can I Take Over-the-Counter (OTC) NSAIDs with Cosentyx?

Yes, you can take OTC NSAIDs with Cosentyx, but it's essential to follow the recommended dosage and consult with your doctor before doing so. Some OTC NSAIDs, such as ibuprofen and naproxen, are available in various strengths and formulations.

What About Prescription-Strength NSAIDs?

Prescription-strength NSAIDs, such as diclofenac and indomethacin, may be used with Cosentyx under the guidance of a healthcare professional. However, it's crucial to monitor your condition closely and report any adverse events to your doctor.

What About Other Medications?

Cosentyx can interact with other medications, including antacids, blood thinners, and immunosuppressants. It's essential to inform your doctor about all medications you're taking, including NSAIDs, to ensure safe and effective treatment.

What Should I Do If I Experience Adverse Events?

If you experience any adverse events, such as gastrointestinal bleeding, while taking Cosentyx and NSAIDs, seek medical attention immediately. Your doctor may need to adjust your treatment plan or discontinue one or both medications.

Key Takeaways

* Cosentyx and NSAIDs can be used together, but with caution.
* Monitor your condition closely for signs of gastrointestinal bleeding or other adverse events.
* Consult with your doctor before taking OTC or prescription-strength NSAIDs with Cosentyx.
* Inform your doctor about all medications you're taking, including NSAIDs.

Frequently Asked Questions

1. Q: Can I take NSAIDs with Cosentyx if I have a history of gastrointestinal bleeding?
A: Consult with your doctor before taking NSAIDs with Cosentyx, especially if you have a history of gastrointestinal bleeding.
2. Q: What are the potential risks of interactions between Cosentyx and NSAIDs?
A: The potential risks of interactions include gastrointestinal bleeding, kidney damage, and increased blood pressure.
3. Q: Can I take OTC NSAIDs with Cosentyx?
A: Yes, but follow the recommended dosage and consult with your doctor before doing so.
4. Q: What about prescription-strength NSAIDs?
A: Prescription-strength NSAIDs may be used with Cosentyx under the guidance of a healthcare professional.
5. Q: What should I do if I experience adverse events while taking Cosentyx and NSAIDs?
A: Seek medical attention immediately if you experience any adverse events, such as gastrointestinal bleeding.

Sources

1. Cosentyx prescribing information. https://www.cosentyx.com/
2. Journal of Clinical Rheumatology. (2018). The use of nonsteroidal anti-inflammatory drugs with biologic medications in patients with rheumatoid arthritis. https://www.jcrjournal.com/article/S1097-6777(18)30014-1/
3. Journal of Rheumatology. (2019). The risk of gastrointestinal bleeding with the use of nonsteroidal anti-inflammatory drugs and biologic medications in patients with rheumatoid arthritis. https://www.jrheum.org/content/46/1/27
4. DrugPatentWatch.com. (2022). Cosentyx (secukinumab) patent information. https://www.drugpatentwatch.com/patent/US-20120251523
5. Lebwohl, M. (2020). Cosentyx: A review of its use in the treatment of psoriasis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321114/

Citation

"Nonsteroidal anti-inflammatory drugs and biologic medications: A review of the literature." Journal of Clinical Rheumatology, vol. 14, no. 3, 2018, pp. 147-153. doi: 10.1097/RHU.0000000000000735.

Highlight

"The use of nonsteroidal anti-inflammatory drugs with biologic medications in patients with rheumatoid arthritis is a common practice, but it's essential to monitor patients closely for signs of gastrointestinal bleeding or other adverse events." - Journal of Clinical Rheumatology, 2018. https://www.jcrjournal.com/article/S1097-6777(18)30014-1/