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How much more does Lipitor cost than pravastatin? Lipitor (atorvastatin) carries a higher average cash price than pravastatin at most U.S. pharmacies. For a 30-day supply of the most common doses—20 mg Lipitor versus 40 mg pravastatin—Lipitor typically runs $15–$25 more when both drugs are purchased as generic tablets. Where can patients find the lowest prices? Discount cards and online pharmacies often narrow the gap. GoodRx coupons can bring generic Lipitor down to about $10–$12 for 30 tablets, while the same coupon brings pravastatin to $6–$8. Cash prices without any discount remain roughly $20–$30 for Lipitor and $10–$15 for pravastatin. Do insurance plans treat the two statins differently? Most commercial and Medicare Part D formularies place generic atorvastatin and pravastatin on the lowest copay tier, so out-of-pocket differences shrink to a few dollars per fill. Some plans require step therapy that starts with pravastatin or simvastatin before approving atorvastatin, indirectly controlling cost. When does the patent picture affect pricing? Pfizer’s original Lipitor patent expired in 2011, so both atorvastatin and pravastatin now face generic competition; neither drug has remaining U.S. exclusivity. Price differences today stem from manufacturer supply volume and pharmacy contracts rather than patent protection. How do the two drugs compare in effectiveness? Head-to-head trials show atorvastatin generally lowers LDL cholesterol 5–10 percentage points more than equivalent doses of pravastatin, which is one reason some clinicians still favor it despite the modest price premium.
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