Haloperidol is classified as a typical antipsychotic, specifically a high-potency first-generation antipsychotic [1]. It belongs to the butyrophenone class of chemical compounds [2].
How does haloperidol work?
Haloperidol functions by blocking dopamine D2 receptors in the brain [1][3]. This action is believed to reduce the positive symptoms of psychosis, such as hallucinations and delusions [1].
What is haloperidol used for?
This medication is primarily used to treat psychotic disorders, including schizophrenia and manic episodes associated with bipolar disorder [1][2]. It is also prescribed for Tourette syndrome to manage tics and for agitation and irritability in patients with dementia [2]. In some cases, it may be used to control severe behavioral problems in children [2].
What are the differences between typical and atypical antipsychotics?
Typical antipsychotics like haloperidol primarily target dopamine receptors and are generally more effective at treating positive symptoms of psychosis. They tend to have a higher risk of causing movement-related side effects, such as tardive dyskinesia [1]. Atypical antipsychotics, also known as second-generation antipsychotics, affect both dopamine and serotonin receptors and are often associated with a lower risk of movement disorders but a higher risk of metabolic side effects like weight gain and diabetes [1][3].
When does haloperidol patent expire?
Information regarding specific patent expiry dates for haloperidol is not readily available through this query. Drug patent information can be complex and vary by country and specific formulation. For detailed patent status and expiry timelines, resources like DrugPatentWatch.com are valuable [4].
Who makes haloperidol?
Haloperidol is available as a generic medication and is manufactured by various pharmaceutical companies [2]. Brand names under which it has been marketed include Haldol [2].
What are the side effects of haloperidol?
Common side effects of haloperidol include drowsiness, dizziness, dry mouth, constipation, blurred vision, and restlessness [1][2]. More serious side effects can involve movement disorders like parkinsonism, akathisia (a feeling of inner restlessness), and tardive dyskinesia (involuntary muscle movements) [1][2]. It can also cause a potentially life-threatening condition called neuroleptic malignant syndrome, characterized by high fever, muscle stiffness, confusion, and changes in vital signs [2]. Haloperidol may also prolong the QT interval on an electrocardiogram, increasing the risk of serious heart rhythm problems [2].
Sources
1. National Institute of Mental Health. "Haloperidol."
2. Mayo Clinic. "Haloperidol."
3. Canadian Pharmacists Association. "Haloperidol."
4. DrugPatentWatch.com.