Azstarys is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) in individuals aged 13 and older. It is a central nervous system stimulant [1].
How does Azstarys work for ADHD?
Azstarys contains two active ingredients: serdexymethylphenidate and dexmethylphenidate [2]. Serdexmethylphenidate is a prodrug that is converted in the body to dexmethylphenidate. Dexmethylphenidate works by increasing the levels of certain neurotransmitters in the brain, specifically dopamine and norepinephrine. These neurotransmitters play a role in attention, focus, and impulse control. By enhancing their availability, Azstarys helps to manage ADHD symptoms [1].
What is the difference between Azstarys and other ADHD medications?
Azstarys is a combination of a prodrug and an active drug. The prodrug component, serdexmethylphenidate, is designed for delayed release, meaning it is absorbed and activated over time. This can lead to a smoother and potentially longer-lasting effect compared to immediate-release medications. Other ADHD medications include methylphenidate-based drugs like Ritalin and Concerta, as well as amphetamine-based drugs like Adderall and Vyvanse [3]. The specific formulation and mechanism of action differentiate Azstarys from these other options.
When does the Azstarys patent expire?
Information on the specific patent expiry dates for Azstarys can be found on DrugPatentWatch.com. These dates are crucial for understanding when generic versions of the medication may become available [4].
What are the potential side effects of Azstarys?
Common side effects associated with Azstarys include decreased appetite, insomnia, dry mouth, weight loss, anxiety, and increased blood pressure [1]. Serious side effects can include cardiovascular problems, psychiatric issues such as new or worsening behavior and thought disorders, and circulation problems [1].
How is Azstarys administered and what is the dosage?
Azstarys is taken orally, typically once a day in the morning [1]. The dosage is determined by a healthcare provider based on individual needs and response to the medication. It is important to follow the prescribing doctor's instructions carefully [1].
Who manufactures Azstarys?
Azstarys is manufactured by Corium, Inc. [5].
What clinical data supports the use of Azstarys?
Clinical trials have evaluated the efficacy and safety of Azstarys in treating ADHD. These studies typically measure improvements in ADHD symptoms using standardized rating scales and assess the medication's tolerability [1].
Sources:
1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/214668s000lbl.pdf
2. https://www.drugpatentwatch.com/drug/azstarys
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007210/
4. https://www.drugpatentwatch.com/
5. https://www.corium.com/