How to Administer Norditropin
Norditropin, a somatropin (human growth hormone) injection, is given subcutaneously once daily using prefilled FlexPro pens or cartridges with needles. Clean the injection site (abdomen, thigh, or upper arm) with an alcohol swab, attach a new needle, dial the prescribed dose, and inject at a 90-degree angle. Rotate sites to avoid irritation. Follow package instructions or doctor guidance for priming the pen and storage.[1][2]
What Dosages Are Used?
Dosing depends on age, weight, and condition:
- Children with growth hormone deficiency: 0.024-0.034 mg/kg/day.
- Adults: 0.004-0.016 mg/kg/day, adjusted based on IGF-1 levels.
Pens come in strengths like 5 mg/1.5 mL, 10 mg/1.5 mL, up to 30 mg/2.5 mL. Start low and titrate slowly.[1][3]
Step-by-Step Injection Guide
1. Wash hands.
2. Check pen for damage; wipe rubber stopper with alcohol.
3. Attach new needle securely.
4. Prime by dialing 2 clicks and holding until a drop appears (do this before first use and if stored over 2 weeks).
5. Dial dose; insert needle into skin fold; press button fully for 6 seconds.
6. Remove needle, discard safely, and recap pen if reusing.
Administer at bedtime for children to mimic natural GH pulses.[2][4]
Storage and Handling Tips
Refrigerate unopened pens at 36-46°F (2-8°C). After first use, store at up to 86°F (30°C) for 28 days (FlexPro) or 4 weeks (NordiFlex), away from light and heat. Do not freeze or shake. Discard if cloudy or discolored.[1][2]
Common Mistakes and How to Avoid Them
Users often forget to prime, leading to underdosing, or reuse needles, risking infection. Always use a new needle per injection and rotate sites every day. If dose is missed, skip it—do not double up.[4][5]
Who Should Not Use It and Side Effects?
Avoid in active cancer, critical illness, or allergy to ingredients. Injection site reactions (redness, pain) occur in 20-40% of users; rare risks include fluid retention or high blood sugar. Monitor with doctor visits.[1][3]
[1]: Norditropin Prescribing Information (Novo Nordisk)
[2]: FDA Label for Norditropin FlexPro
[3]: Novo Nordisk Patient Instructions
[4]: Medscape Dosing Guide
[5]: Drugs.com Administration FAQ