What patent applications cover sitagliptin and transaminase (liver enzyme) findings on Google Patents?
Sitagliptin is a DPP-4 inhibitor, and “transaminase” typically refers to liver enzymes such as ALT/AST. To find the specific Google Patents application(s) you mean, the fastest approach is to run targeted searches using combinations of these terms in Google Patents:
- “sitagliptin” AND “transaminase”
- “sitagliptin” AND “ALT”
- “sitagliptin” AND “AST”
- “sitagliptin” AND “alanine aminotransferase”
- “sitagliptin” AND “aspartate aminotransferase”
- “DPP-4” AND “transaminase” (sometimes filings describe the class rather than the specific enzyme terms)
Use Google Patents’ advanced search operators (e.g., title/abstract claims scope) to narrow results, because “transaminase” may appear only in the description of safety/toxicity or liver-monitoring data, not in the claims.
How do you search Google Patents effectively for “transaminase” language?
In Google Patents, try switching between:
- General search box terms: “sitagliptin transaminase”
- Title/abstract-focused terms (via field restrictions in Google Patents’ query syntax)
- Phrase search: “transaminase” (with or without “elevated,” “increase,” “monitoring,” “hepatic”)
Then sort by relevance and open the most relevant documents to check whether “transaminase” is used in:
- dosing/regimen claims,
- monitoring steps (e.g., measuring ALT/AST),
- safety claims about reducing or avoiding transaminase elevation,
- clinical examples tied to liver enzyme outcomes.
Are there patent filings that link sitagliptin to liver-enzyme elevations or hepatotoxicity monitoring?
Many pharmaceutical patent documents that include clinical or safety data mention liver enzymes as part of adverse-event reporting, even when the core invention is not “for transaminase.” If your goal is “sitagliptin transaminase” specifically, the results you want are usually those that include:
- safety endpoints mentioning ALT/AST,
- adverse-event language about “elevations,”
- monitoring regimens in treatment methods.
The key is to identify whether “transaminase” appears as an invention feature (in claims) or only as background/experimental results (in the description).
What to do if you only need the application number or publication link?
Once you find a candidate result on Google Patents, capture:
- Publication number (WO…, US… publication, EP… publication, etc.)
- Application number (if shown)
- Assignee/applicant
- Earliest priority date
- The exact section where transaminase terms appear (abstract/claims/description)
If you share the publication number(s) you’re seeing (or paste the Google Patents URL), I can tell you whether the filing’s claims actually address transaminase/liver-enzyme outcomes or just reference them in clinical data.
If you meant a specific phrase: “transaminase” vs “ALT/AST”?
Some filings use “hepatic transaminase,” “transaminase levels,” or “aminotransferase,” while others list specific enzyme names (ALT/AST) without the word “transaminase.” If searches for “transaminase” return few results, rerun with:
- “aminotransferase”
- “alanine aminotransferase”
- “aspartate aminotransferase”
- “hepatic” AND “enzyme” AND “sitagliptin”
Sources I can use (and what I need from you)
I don’t yet have the exact Google Patents entry you’re referring to, so I can’t point to a specific sitagliptin/transaminase application without more details.
If you paste either:
1) the Google Patents search results link you used, or
2) one candidate publication number (e.g., “US 20xx/xxxxx”),
I’ll extract the relevant transaminase-related content and confirm what the patent is actually claiming.
Sources
None cited yet (no specific Google Patents documents were provided).