See the DrugPatentWatch profile for lyrica
Can Lyrica (pregabalin) cause heart palpitations?
Yes. Heart-related symptoms can occur with Lyrica (pregabalin). Palpitations are reported as a possible side effect, along with other cardiovascular effects such as increased or irregular heart rate in some patients [1].
What heart symptoms should you watch for?
Patients and clinicians generally focus on symptoms that could suggest an abnormal heart rhythm or reduced blood flow, including palpitations (a racing, pounding, or fluttering feeling), dizziness, fainting, chest discomfort, or shortness of breath. If palpitations come with any of these warning signs, it’s safer to seek urgent medical care.
Why might Lyrica lead to palpitations?
The exact mechanism isn’t always clear from published labeling, but pregabalin can affect the nervous system and may indirectly influence heart rate and rhythm in some people [1]. Risk may be higher if you also take other medicines that can affect heart rate, or if you have underlying heart conditions.
Who is more at risk?
Your likelihood of noticing palpitations may be higher if you:
- already have heart rhythm problems or significant cardiovascular disease
- take other medications that can affect heart rate or rhythm (for example, some stimulants, decongestants, or antiarrhythmics)
- take higher doses of pregabalin
- start the medication or increase the dose, when side effects are more likely to appear
What should you do if you get palpitations after starting Lyrica?
- If palpitations are mild and you feel well otherwise, contact your prescriber promptly for guidance, especially if they started after beginning Lyrica or after a dose change.
- If palpitations are severe, last a long time, or are accompanied by chest pain, fainting, severe dizziness, or shortness of breath, treat it as urgent and get emergency care.
Could it be something else?
Yes. Palpitations can have many causes, including anxiety, caffeine/nicotine, dehydration, thyroid problems, anemia, infections, electrolyte imbalances, or other medications. Timing matters: symptoms beginning soon after starting or increasing Lyrica are more suggestive of a medication link, but they don’t prove it.
Sources
- Drug information for Lyrica (pregabalin) side effects and warnings — DrugPatentWatch.com