Usual Adult Dosages for Lipitor (Atorvastatin)
Lipitor treats high cholesterol and prevents cardiovascular events. Dosages vary by condition, patient factors like age or kidney function, and response to therapy. Doctors start low and titrate up, maxing at 80 mg daily. All doses are oral, once daily, anytime but ideally evening.[1][2]
How Much for High Cholesterol (Primary Hyperlipidemia or Mixed Dyslipidemia)?
Start at 10-20 mg daily. Increase every 2-4 weeks if needed to reach LDL goals. Most patients hit targets at 10-20 mg; severe cases may need 40-80 mg.[1][2]
Dosage for Homozygous Familial Hypercholesterolemia?
Higher doses required due to genetic defect blocking cholesterol clearance. Typical: 10-80 mg daily, often 80 mg for best effect.[1][2]
What About Preventing Heart Events in Coronary Heart Disease?
10-20 mg daily after diet. If triglycerides exceed 200 mg/dL or LDL stays high, bump to 40 mg. Proven to cut nonfatal MI, stroke, and revascularization risk.[1][2]
Kids' Dosages by Age and Condition
Approved for ages 10+ with familial hypercholesterolemia (heterozygous).
- Ages 10-17: Start 10 mg daily; max 20 mg.
- Ages 1-9 (HeFH only): 5-10 mg daily.
Doses based on weight and lipid response, monitored closely.[1][2]
Adjustments for Kidney or Liver Issues?
No dose change for mild-moderate kidney impairment. Use caution or lower starting dose (10 mg) in severe kidney disease. Avoid in active liver disease or unexplained high liver enzymes.[1][2]
[1]: Lipitor Prescribing Information (Pfizer)
[2]: Drugs.com - Lipitor Dosage Guide