What's the common methotrexate dose for adults?

Methotrexate dosing depends a lot on what it’s being used for (e.g., rheumatoid arthritis/psoriasis vs. cancer), so there isn’t one single “common” adult dose.

Common adult dosing (non-cancer uses)

Rheumatoid arthritis / psoriasis (usually weekly dosing):

• Typical starting dose: 7.5–15 mg by mouth once weekly
• Common range: 15–25 mg once weekly
• Some patients may go higher under close supervision, often up to 25–30 mg/week depending on response and tolerability.

Important safety note: In arthritis/psoriasis, methotrexate is almost always taken once per week, not daily.

Cancer dosing

Cancer regimens vary widely (sometimes much higher and/or more frequent dosing, often with “leucovorin rescue”), so doses are regimen-specific.

If you tell me the indication (RA, psoriasis, ectopic pregnancy, cancer type, etc.) and whether it’s oral vs injection, I can give the most relevant typical adult dose range.