Can artesunate be administered orally?

Can artesunate be administered orally?

Yes, artesunate is available in oral tablets. It is commonly used in fixed-dose combination therapies with other antimalarial drugs such as amodiaquine, mefloquine, or pyronaridine.

What oral formulations exist?

Oral artesunate is sold alone or as a co-blistered pack with a partner drug. These products meet WHO prequalification standards for malaria treatment in endemic regions.

How does oral administration compare with intravenous use?

Oral administration is suitable for uncomplicated malaria cases. Intravenous artesunate remains the treatment of choice for severe malaria, where rapid blood-level spikes are needed.

Why do patients and programs prefer oral routes?

Oral tablets simplify logistics, eliminate needle-related risks, and allow patients to complete treatment at home. They cost less than intravenous preparations and are easier to store without refrigeration.

When does oral artesunate patent protection end?

Key patents on artesunate itself have expired. Generic oral formulations are widely available from multiple manufacturers.