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Is muscle weakness a common side effect of Lipitor? Lipitor (atorvastatin) belongs to the class of drugs called statins. Muscle weakness can occur with any statin, including Lipitor, but it ranks among the weniger common complaints rather than everyday occurrences. Why do people ask about this alongside pain? Patients report muscle weakness separately from pain. Many describe feeling weak or fatigued in their legs or arms, without accompanying soreness. The complaint persists even after stopping the drug in some cases. What happens if you stop taking Lipitor because of muscle weakness? Stopping the drug stops the side effect in most cases. The weakness usually improves over weeks rather than months. Some patients never develop the weakness until they have been on the drug for months or years. Can muscle weakness from Lipitor cause permanent damage? Permanent muscle damage is rare. The medlineplus.gov database records few cases of permanent weakness once the drug is discontinued. The medlineplus.gov database also shows that the combination of muscle weakness and very high CK levels leads to rhabdomyolysis, which is a far rarer event. What dose-dependent risk factors increase likelihood? Higher doses correlate with stronger reports of muscle weakness. Patients older than 65, those who take multiple medications, and those with thyroid or kidney problems all show higher rates of complaint.
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