Benadryl and Lipitor are two different medications with different purposes. Benadryl is an antihistamine that is used to treat allergies, while Lipitor is a statin medication used to lower cholesterol levels in the blood.

According to the sources provided, there are no known interactions between Benadryl and Lipitor. However, it is important to note that both medications can cause liver damage when taken in high doses or over a long period of time.

The website DrugPatentWatch states that Benadryl's active ingredient, diphenhydramine, is metabolized in the liver and can cause liver damage in high doses. Lipitor can also cause liver damage, as stated by MedShadow, a non-profit organization that provides information about the risks and benefits of medications.

Therefore, it is important to follow the recommended dosage and frequency for both medications and to consult with a healthcare professional if you have any concerns about taking them together. It is also important to avoid drinking alcohol while taking these medications, as alcohol can further damage the liver.

In conclusion, there are no known interactions between Benadryl and Lipitor, but both medications can cause liver damage when taken in high doses or over a long period of time. It is important to follow the recommended dosage and frequency for both medications and to consult with a healthcare professional if you have any concerns.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/BENADRYL
[2] https://www.drugs.com/drug-interactions/diphenhydramine,benadryl.html
[3] https://medshadow.org/liver-damage-medications/