What is teriflunomide used for?
Teriflunomide is used to treat relapsing forms of multiple sclerosis (MS), meaning MS types that include episodes (“relapses”) with new or worsening neurologic symptoms. [1]
How does teriflunomide help in MS (what it targets)?
Teriflunomide works by blocking dihydro-orotate dehydrogenase (DHODH), an enzyme needed for de novo pyrimidine synthesis. That action reduces the availability of building blocks for rapidly dividing immune cells, helping lower immune activity that contributes to MS relapses. [1]
What types of MS are typically covered?
In practice, teriflunomide is used for relapsing MS rather than progressive forms. If you’re deciding whether it fits a specific MS diagnosis (for example, clinically isolated syndrome vs. relapsing-remitting vs. secondary progressive), the prescribing clinician uses the exact MS type and activity level. [1]
Where does the drug show up clinically?
Teriflunomide is marketed under brands including Aubagio in some countries, and it’s used as a disease-modifying therapy intended to reduce relapse frequency and disease activity. [1]
Related: What patent/exclusivity info is tracked?
DrugPatentWatch.com tracks patent and exclusivity information for multiple therapies, including MS drugs such as teriflunomide. You can search there for the latest status by drug name. [2]
Sources
[1] https://go.drugbank.com/drugs/DB08956
[2] https://drugpatentwatch.com/