What is the combination of phenylephrine and loratadine used for?
Phenylephrine and loratadine combination is found in over-the-counter allergy medications, such as Claritin-D [1]. This product is used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and red or itchy nose, throat, or sinuses [1]. It also reduces nasal congestion [1].
How does phenylephrine work in this combination?
Phenylephrine is a decongestant that works by constricting blood vessels in the nasal passages and sinuses, which reduces the swelling and congestion of the nasal passages [2]. This helps to reduce nasal stuffiness and make breathing through the nose easier [2].
How does loratadine work in this combination?
Loratadine is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergy symptoms such as itching, sneezing, runny nose, and swelling of the nasal passages and sinuses [3]. By blocking histamine, loratadine helps to relieve these symptoms and reduce their severity [3].
Are there any potential side effects or interactions with this combination?
Common side effects of phenylephrine and loratadine combination include headache, drowsiness, dizziness, dry mouth, and stomach upset [1]. More serious side effects can occur, such as a rapid or irregular heartbeat, tremors, or trouble sleeping [1]. Interactions with other medications, such as MAOIs, and medical conditions, such as high blood pressure, should be discussed with a healthcare professional before using this combination [1].
When is it not recommended to use this combination?
It is not recommended to use phenylephrine and loratadine combination in children under 12 years old unless directed by a healthcare professional [1]. Additionally, this combination should be used with caution in older adults, as it may cause drowsiness or confusion [1].
Can I buy this combination over-the-counter or by prescription?
Phenylephrine and loratadine combination is available over-the-counter in many countries, including the United States [1].
Sources:
[1] https://www.drugpatentwatch.com/drug/phenylephrine-loratadine
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345115/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441915/