Standard Adult Dosage for Pain or Fever
Take 325-650 mg every 4-6 hours as needed. Do not exceed 4 grams (4,000 mg) in 24 hours.[1]
Daily Use for Heart Attack or Stroke Prevention
Low-dose aspirin (81 mg or 325 mg) once daily. Use only under doctor guidance for long-term prevention.[1][2]
Children's Dosing by Age and Weight
Avoid aspirin in children under 16 due to Reye's syndrome risk, except as directed by a doctor. For ages 2-11, dose is typically 10-15 mg per kg every 4-6 hours, max 60 mg/kg daily.[1]
Maximum Frequency Limits
- Short-term (pain relief): Up to 4-6 doses per day, spaced 4 hours apart.
- Do not take more often than recommended to avoid overdose.[1]
Risks of Taking Too Often
Frequent or high doses raise chances of stomach bleeding, ulcers, kidney damage, or allergic reactions. Stop and seek medical help for signs like black stools, vomiting blood, or severe stomach pain.[1][2]
Who Should Limit or Avoid Frequent Use
Pregnant people (especially third trimester), those with ulcers, asthma, bleeding disorders, or on blood thinners should consult a doctor first. Not for routine use without advice.[1][2]
When to Talk to a Doctor Before Regular Use
Always check if you have health conditions, take other meds, or plan long-term use. Enteric-coated versions may reduce stomach irritation but don't change frequency rules.[1]
[1]: FDA Aspirin Labeling
[2]: Mayo Clinic Aspirin Guidelines