Based on the information available, there is no evidence to suggest that a dosage change of Lipitor (atorvastatin) is needed when taken in conjunction with iron supplements. According to Drugs.com, there are no known interactions between atorvastatin and iron salts. However, it is always advisable to consult with a healthcare provider or pharmacist before starting any new medications or supplements, as individual responses to medications can vary [1].

It is also important to note that Lipitor is primarily metabolized by the liver through the cytochrome P450 3A4 isoenzyme system, and its clearance can be affected by other medications that inhibit or induce this enzyme system [2]. Iron supplements do not have a known effect on this metabolic pathway.

In summary, based on the available information, there is no need to adjust the dosage of Lipitor when taken with iron supplements. However, it is always recommended to consult with a healthcare provider or pharmacist before starting any new medications or supplements.

Sources:

1. Atorvastatin (Oral Route) Interactions - Drugs.com. (n.d.). Retrieved from <https://www.drugs.com/drug-interactions/atorvastatin-oral-route-with-iron-salts-oral-route.html>
2. Atorvastatin - DrugBank. (n.d.). Retrieved from <https://go.drugbank.com/drugs/DB00335#metabolism>
3. DrugPatentWatch. (n.d.). Retrieved from <https://www.drugpatentwatch.com/>