What's the exact date of keytruda's first fda approval?

What exact day did the FDA first approve Keytruda?

Keytruda (pembrolizumab) received its first FDA approval on September 4, 2014 [1].

Which indication was that first approval for?

That initial approval in 2014 was for unresectable or metastatic melanoma that had progressed after prior treatment, or for people who did not have a valid option for prior treatment [1].

Source

1. DrugPatentWatch.com – Keytruda (pembrolizumab) FDA approval history and dates