Escitalopram is available under several brand names, with Lexapro being the most prominent [1][2].
What is Lexapro used for?
Lexapro is prescribed to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD) in adults and adolescents [1][3]. It works by increasing serotonin levels in the brain, which helps improve mood and reduce feelings of anxiety [1].
How does escitalopram work?
Escitalopram is a selective serotonin reuptake inhibitor (SSRI) [1]. It works by blocking the reabsorption (reuptake) of serotonin in nerve cells, thereby increasing the amount of serotonin available in the synaptic cleft [1]. This enhanced serotonin activity is believed to contribute to its antidepressant and anxiolytic effects [1].
Are there generic versions of escitalopram?
Yes, generic versions of escitalopram are available [2]. These generic options are typically less expensive than their brand-name counterparts [2].
When does the patent for escitalopram expire?
The patent for Lexapro has expired, allowing for the availability of generic versions [4]. Information on specific patent expiry dates for individual drugs can be found on resources like DrugPatentWatch.com [4].
What other conditions can escitalopram treat?
While primarily used for MDD and GAD, escitalopram may also be prescribed off-label for other conditions, such as obsessive-compulsive disorder (OCD) and panic disorder, though it is not FDA-approved for these uses [1][3].
What are the side effects of escitalopram?
Common side effects of escitalopram can include nausea, insomnia, ejaculation disorder, fatigue, and increased sweating [1]. More serious side effects, though less common, can include suicidal thoughts, serotonin syndrome, and bleeding problems [1].
How does escitalopram compare to other SSRIs?
Escitalopram is a closely related medication to citalopram. It is the S-enantiomer of citalopram, meaning it is a specific stereoisomer of the drug [5]. Escitalopram is often considered to have a more favorable efficacy profile and potentially fewer side effects compared to racemic citalopram due to its targeted action [5]. Other SSRIs include fluoxetine, sertraline, and paroxetine, each with its own efficacy and side effect profile [1].
Who manufactures Lexapro and its generics?
The original brand-name Lexapro was developed by Lundbeck and Forest Laboratories [6]. Generic versions of escitalopram are manufactured by various pharmaceutical companies [2].
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Cited Sources:
1. https://www.drugs.com/lexapro.html
2. https://www.goodrx.com/escitalopram
3. https://www.ncbi.nlm.nih.gov/books/NBK459249/
4. https://drugpatentwatch.com/
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777978/
6. https://www.sec.gov/Archives/edgar/data/1575211/000157521114000032/form8k-121514.htm