Vismodegib?

Vismodegib (brand name Erivedge) is a medication used to treat certain types of basal cell carcinoma (BCC).

What it’s used for

• Locally advanced BCC that is not a candidate for surgery or radiation
• Metastatic BCC

How it works

• Vismodegib is a hedgehog pathway inhibitor (it targets SMO, a key component of the hedgehog signaling pathway), which helps slow or stop tumor growth.

How it’s usually taken

• Typically taken by mouth once daily
• It’s often continued as long as it’s working and side effects are manageable (Exact dosing depends on the prescribed regimen and tolerability.)

Common side effects

• Muscle spasms/cramps
• Loss of appetite
• Weight loss
• Fatigue
• Nausea
• Hair loss (alopecia)
• Taste changes

Important safety notes

• Pregnancy/birth defect risk: Vismodegib can cause severe fetal harm. Effective contraception is required during treatment and for a period after stopping (for both females and males per prescribing guidance).
• Not for everyone: Your clinician will consider liver/kidney function, other meds, and overall health.
• Monitoring: Weight, muscle symptoms, and general tolerability are commonly monitored.

Drug interactions (practical)

• Vismodegib can interact with other medicines that affect metabolism/transport systems—so it’s important to review your full medication list (including supplements).

If you tell me what you need—e.g., side effects, dosing, how long it takes to work, pregnancy precautions, or interactions—I can tailor the info.