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Does dairy affect how well Lipitor works? Lipitor is a statin that lowers cholesterol by blocking an enzyme in the liver. Dairy products do not directly interfere with its effectiveness. However, some dairy foods high in fat or calcium can change the amount of atorvastatin—the active ingredient in Lipitor—that the body absorbs. What happens if you take Lipitor with milk? Milk contains calcium, which can bind to certain medications and reduce their absorption. Atorvastatin does not bind significantly to calcium, so milk does not substantially alter its blood levels. The official prescribing information for Lipitor does not list dairy as a restriction. Can high-fat dairy change Lipitor's blood levels? High-fat meals can increase the amount of atorvastatin absorbed by about 20 percent. This small increase does not require dose adjustment or timing changes. Most doctors advise taking Lipitor at any time of day, regardless of meals. Why are some people asking about dairy and Lipitor? People may confuse Lipitor with tetracycline antibiotics or bisphosphonates, which are known to interact with calcium in dairy. Those drugs require separation from dairy by two hours or more. Lipitor has no such rule. How does Lipitor's patent status affect alternatives? Lipitor's patent expired in 2011, making generic atorvastatin widely available. Generic versions work the same way and interact with dairy in the same way as the brand-name drug.
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