Advil is a brand name for the drug ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. According to Drugs.com [2], Advil can be taken with or without food. However, taking ibuprofen on an empty stomach can increase the risk of gastrointestinal side effects such as stomach upset, nausea, and bleeding [2, 3]. Therefore, it is recommended to take Advil with food or a full glass of water to minimize the risk of stomach irritation [3]. It is also important to follow the recommended dosage and not to exceed the maximum daily dose of 1200mg for adults [2]. Additionally, it is important to consult a healthcare provider before taking Advil if you have a history of stomach ulcers, bleeding disorders, or kidney disease [3].

Sources:
[2] "Can you take ibuprofen on an empty stomach?" Drugs.com. Accessed on September 22, 2021. https://www.drugs.com/medical-answers/you-ibuprofen-empty-stomach-3572019/
[3] "Can You Take Ibuprofen on an Empty Stomach?" Healthline. Accessed on September 22, 2021. https://www.healthline.com/health/ibuprofen-on-empty-stomach