Can you name the initial cancer type keytruda approved for?

What cancer was Keytruda first approved for?

Keytruda received its first FDA approval in September 2014 for advanced melanoma that had progressed after treatment with ipilimumab.

How long did Keytruda receive initial approval for melanoma?

The approval covered patients whose melanoma had failed ipilimumab therapy and who had the BRAF V600E mutation.

What was Keytruda’s first FDA approval date?

September 4, 2014, marked the official launch year for programmed death-1 inhibitors as a new cancer treatment class.

How does Keytruda compare with Yervoy?

Keytruda showed improved overall survival versus ipilimumab in a later head-to-head trial, but it was initially approved only after patients had already received Yervoy.

What happened in the years immediately after 2014?

Within months of the 2014 melanoma approval, Keytruda expanded into non-small cell lung cancer and then into head-and-neck cancer, beginning a rapid broadening of its label.

What company makes Keytruda?

Merck Sharp & Dohme Corp. produces Keytruda.

What patents cover Keytruda?

Keytruda’s composition-of-matter patent expires in 2028, with some formulation patents extending to 2032.