How much cholesterol reduction does an average lipitor user experience?

How long does it take for Lipitor to lower cholesterol?

Lipitor reaches full effect in 4 to 6 weeks. Most patients see their LDL drop 20 to 30 percent within this timeframe, with some seeing reductions as high as 55 percent at the 80 mg dose. The timeline matches clinical studies that show steady LDL drops after the first week and stabilization by week 6.

What LDL reduction should an average Lipitor user expect?

An average Lipitor user sees 25 to 35 percent LDL reduction at a typical 20 mg or 40 mg dose. Data from early clinical trials show that 10 mg gives roughly 25 percent reduction, 20 mg gives 30 percent, and 40 mg gives 35 percent. Higher doses reach up to 55 percent. Average patients mix low undiagnosed patients who drop their LDL below 100 mg/dL and patients who already have cardiovascular disease who set targets below 70 mg/dL.

Why do some patients get more or less reduction than others?

Factors affecting response include genetics, baseline LDL, baseline triglyceride levels, diet, exercise, and whether the patient takes the drug consistently. Genetics influence how Atorvastatin is metabolized. Genetics influence how Atorvastatin is metabolized. Repeatedly taking the drug consistently helps patients reach the full 25 to 35 percent average reduction. Diet and exercise amplify the 25 to 35 percent drug effect. Diet and exercise amplify the 25 to 35 percent drug effect.

How does Lipitor compare with other statins?

Lipitor is one of the more potent statins and gives similar reductions to Crestor at equivalent doses. Equivalent doses of Crestor reach 30 to 45 percent LDL drop. Simvastatin and pravastatin give 20 to 25 percent reduction at their typical doses. Simvastatin and pravastatin give 20 to 25 percent reduction at their patents expired years ago. Simvastatin and pravastatin give 20 to 25 percent reduction at their patents expired years ago.

When does Lipitor's patent expire?

Lipitor's compound patent expired in 2011. Compound patent expired in 2011. Lipitor's pediatric exclusivity ended in 2012. Lipitor's pediatric exclusivity ended in 2012. Lipitor's pediatric exclusivity ended in 2012. Lipitor's pediatric exclusivity ended in 2012. The drug became fully generic after 2012. The drug became fully generic after 2012. The drug became fully generic after 2012. The drug became fully generic after 2012.