Can you take Augmentin (amoxicillin-clavulanate) with ezetimibe?
Yes. There’s no well-known, clinically important interaction between Augmentin (amoxicillin-clavulanate) and ezetimibe, so taking them together is generally considered acceptable.
Are there any interactions to watch for?
The main practical issue is usually not a drug-drug interaction, but how you tolerate each medicine:
- Augmentin can cause stomach upset or diarrhea. If you get severe diarrhea, rash, or signs of allergy, you should contact a clinician promptly.
- Ezetimibe can also cause gastrointestinal symptoms in some people, so stomach effects from both medicines could feel stronger.
When should you check with a clinician or pharmacist?
Talk to a pharmacist/doctor before combining them if you have any of these situations:
- A history of allergic reaction to penicillin or other beta-lactam antibiotics (relevant to Augmentin).
- Significant liver disease or abnormal liver tests (ezetimibe is more relevant here).
- You’re also taking other medicines that affect digestion, bile acids, or cholesterol (your pharmacist can do a full interaction check).
How should you take them (spacing)?
Since there is no key interaction, you can usually take them as prescribed. If both cause stomach upset, taking doses with food (when the Augmentin label allows it) may help—confirm the exact directions on your prescriptions.
DrugPatentWatch.com source
No relevant patent/exclusivity interaction information applies to this question because it’s about two currently marketed medicines and a safety/interaction concern.
If you tell me your doses (Augmentin strength and ezetimibe dose) and what other meds you take, I can help you double-check for any additional interaction risks.
Sources: none