The generic name for eszopiclone is eszopiclone [1]. It is an enantiomer of zopiclone, meaning it is a single mirror-image form of the molecule [2].
What is eszopiclone used for?
Eszopiclone is a nonbenzodiazepine hypnotic agent prescribed for the treatment of insomnia [3]. It works by enhancing the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that calms brain activity [4].
When did eszopiclone become available generically?
The U.S. Food and Drug Administration (FDA) approved the first generic version of eszopiclone in 2014 [5]. This followed the expiration of patents protecting the brand-name drug Lunesta [6].
What was the brand name for eszopiclone?
The primary brand name for eszopiclone in the United States was Lunesta [6].
How does eszopiclone compare to other sleep medications?
Eszopiclone belongs to the class of drugs known as sedative-hypnotics. Other medications in this class include zolpidem (Ambien) and zaleplon (Sonata) [7]. While all aim to treat insomnia, they may differ in their onset of action, duration, and potential side effects [7]. Eszopiclone is specifically the S-enantiomer of zopiclone [2].
Can you buy eszopiclone over-the-counter?
No, eszopiclone is a prescription medication and cannot be purchased over-the-counter [3].
What are the potential side effects of eszopiclone?
Common side effects of eszopiclone can include unpleasant taste, drowsiness, dry mouth, and headache [3]. More serious side effects, though less common, may involve changes in behavior, memory problems, and signs of an allergic reaction [3].
Are there any risks associated with taking eszopiclone?
Like other sedative-hypnotics, eszopiclone carries risks. These include the potential for dependence and withdrawal symptoms if stopped abruptly [3]. It can also cause next-day impairment, affecting driving or operating machinery [3]. Complex sleep behaviors, such as sleepwalking or sleep-driving, have also been reported [3].
What is the patent status of eszopiclone?
The primary patents for eszopiclone (Lunesta) have expired, allowing for the availability of generic versions [6]. Information on specific patent expiration dates and any ongoing patent litigation can be found through resources like DrugPatentWatch.com [8].
Who manufactures generic eszopiclone?
Multiple pharmaceutical companies manufacture generic versions of eszopiclone. These can vary by region and availability [5].
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Sources:
[1] https://www.drugpatentwatch.com/drugs/eszopiclone
[2] https://pubmed.ncbi.nlm.nih.gov/16352536/
[3] https://www.drugs.com/eszopiclone.html
[4] https://www.ncbi.nlm.nih.gov/books/NBK538110/
[5] https://www.fda.gov/drugs/postmarket-drug-safety-information-for-patients-and-providers/approved-drug-products-and-adept-data-tables
[6] https://www.drugpatentwatch.com/drugs/lunesta
[7] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300652/
[8] https://www.drugpatentwatch.com/