Prolia sq injection?

What is Prolia SQ Injection?

Prolia SQ injection, also known as denosumab, is a prescription medicine used to treat osteoporosis in women and men who are at high risk of fracture. It is also used to treat bone loss in people with prostate cancer, to treat bone loss in people with breast cancer, and to treat multiple myeloma and hypercalcemia (high levels of calcium in the blood) secondary to parathyroid carcinoma.

How Does Prolia SQ Injection Work?

Prolia SQ injection works by blocking the action of a protein called RANKL, which is involved in the development of bone-destroying cells called osteoclasts. By blocking RANKL, Prolia SQ injection reduces the activity of osteoclasts, which can help to slow down or stop bone loss.

What are the Benefits of Prolia SQ Injection?

The benefits of Prolia SQ injection include:

* Increased bone density: Prolia SQ injection can help to increase bone density in people with osteoporosis, which can reduce the risk of fractures.
* Reduced fracture risk: Studies have shown that Prolia SQ injection can reduce the risk of fractures in people with osteoporosis.
* Improved quality of life: Prolia SQ injection can help to improve quality of life by reducing the risk of fractures and other complications associated with osteoporosis.

Side Effects of Prolia SQ Injection

Common side effects of Prolia SQ injection include:

* Joint pain
* Muscle pain
* Fatigue
* Osteonecrosis of the jaw (necrosis of the bone tissue in the jaw)
* Atypical subtrochanteric fractures of the femur (fractures of the thigh bone)
* Skin reactions

Who Should Not Take Prolia SQ Injection?

Prolia SQ injection is not recommended for people with certain medical conditions, including:

* Hypocalcemia (low levels of calcium in the blood)
* Hypophosphatasia (a rare genetic disorder)
* Paget's disease of bone
* Malignant hypercalcemia (high levels of calcium in the blood due to cancer)
* Osteonecrosis of the jaw

Pricing and Availability

Prolia SQ injection is available in a 60 mg/mL solution for injection in pre-filled syringes. The cost of Prolia SQ injection can vary depending on the pharmacy and insurance coverage.

Patent Information

Prolia SQ injection is manufactured by Amgen and has a patent that expires in 2029.

Sources:

[1] Amgen. (n.d.). Prolia (Denosumab) Injection. Retrieved from https://www.amgen.com/-/media/amgen/commercial-products/prolia

[2] Prolia (Denosumab) - FDA Labeling. (n.d.). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/125320lbl.pdf

[3] DrugPatentWatch.com. (n.d.). Prolia [Denosumab]. Retrieved from https://www.drugpatentwatch.com/dose/form/60/