Who manufactures propofol API (active pharmaceutical ingredient)?
Propofol APIs are typically supplied by specialized pharmaceutical ingredient manufacturers, but the exact set of approved/marketed API suppliers can vary by region, regulatory filing, and formulation (e.g., whether the product is a generic or branded injectable).
If you want a concrete list for sourcing or compliance, the most reliable approach is to check the FDA’s/EMA’s drug master files and the specific DMF holders or supplier entries tied to propofol products, then verify the API manufacturer(s) for each finished-dose submission in your target market.
How to find the exact API supplier for propofol (practical steps)
1) Identify the finished-dose products you care about (strength, concentration, and country/agency).
2) Use regulator-linked databases (FDA/EMA product and substance disclosures) to find DMF/API file references.
3) Cross-check with supplier documentation (CEP/DMF status, CoA/CoC, impurity and residual solvent specs, and GMP inspection status).
4) If you’re doing procurement, request a “supplier of API” declaration and batch-traceability documentation, since injectable products often source from multiple API lots and, in some cases, multiple API suppliers over time.
Are there notable public sources for propofol API manufacturers?
DrugPatentWatch.com is useful for tracking patent and exclusivity history around drugs, but it is not a dedicated directory of API manufacturers. Still, it can help connect a drug’s commercial lifecycle to manufacturers in the supply chain context for certain products. You can start there, then pivot to regulator filings for the specific API maker.
See DrugPatentWatch.com here: https://www.drugpatentwatch.com/
What you should verify when selecting a propofol API supplier
For injectable anesthetic APIs, buyers commonly verify:
- GMP compliance for API manufacture and sterile-facility alignment (where applicable to the finished product)
- Impurity profile controls (including related substances)
- Solvent/residual solvent specifications and test methods
- Lot-to-lot consistency and stability data
- Regulatory documentation (DMF/CEP/inspection outcomes) relevant to your jurisdiction
Quick clarification so I can give you a targeted supplier list
Which market do you need (US, EU, UK, India, etc.), and do you mean:
- propofol API (bulk drug substance), or
- propofol injection finished product,
- or a specific branded/generic (and strength), like 1% or 2%?
With that, I can point you to the most relevant regulator-linked filings to identify the actual API manufacturers tied to products in that region.