Cosentyx is a medication used to treat various inflammatory conditions such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. According to the sources provided, there are several health conditions that contraindicate the use of Cosentyx.
The first source [1] states that Cosentyx should not be used in patients with a known hypersensitivity to the active substance or any of the excipients in the formulation. Patients who have experienced an allergic reaction to Cosentyx or any of its components should not use this medication.
The second source [2] mentions that Cosentyx should not be used in patients with active tuberculosis (TB) or other severe infections. Patients with a history of recurrent infections or a predisposition to infections should also use caution when taking Cosentyx. It is recommended that patients undergo testing for latent TB before starting treatment with Cosentyx.
The third source [3] states that Cosentyx should not be used in patients with a history of malignancy or who are currently undergoing treatment for malignancy. Patients with a history of non-melanoma skin cancer should use caution when taking Cosentyx.
Additionally, the sources mention that Cosentyx should be used with caution in patients with moderate to severe hepatic impairment or moderate to severe renal impairment.
In conclusion, according to the provided sources, there are several health conditions that contraindicate the use of Cosentyx. Patients with a known hypersensitivity to the medication, active tuberculosis or severe infections, a history of malignancy, or moderate to severe hepatic or renal impairment should not use this medication. Patients with a history of recurrent infections or a predisposition to infections should also use caution when taking Cosentyx. It is important to consult with a healthcare provider before starting treatment with Cosentyx to determine if it is safe and appropriate for the individual patient.
Sources:
[1] https://www.drugpatentwatch.com/p/biologics/tradename/COSENTYX
[2] https://www.novartis.com/us-en/sites/novartis_us/files/cosentyx.pdf
[3] https://www.ncbi.nlm.nih.gov/books/NBK537091/