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What are the potential interactions with lurbinectedin?



Lurbinectedin is a medication used to treat metastatic small cell lung cancer (SCLC) in adults who have received previous treatment [2]. As with any medication, there are potential interactions that patients should be aware of before taking Lurbinectedin.

According to Drug Patent Watch [1], there are no known drug interactions with Lurbinectedin at this time. However, it is always important to inform your doctor of any medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, as they may interact with Lurbinectedin.

Medscape [2] notes that Lurbinectedin is metabolized by the liver, so caution should be taken when administering Lurbinectedin to patients with liver impairment. Additionally, Lurbinectedin may cause QT prolongation, a heart rhythm disorder, and should be used with caution in patients with a history of QT prolongation or other heart conditions.

The Mayo Clinic [3] lists some common side effects of Lurbinectedin, including nausea, fatigue, and low white blood cell count. Patients taking Lurbinectedin should inform their doctor if they experience any unusual side effects or symptoms.

In summary, while there are currently no known drug interactions with Lurbinectedin, patients should still inform their doctor of any medications they are taking. Lurbinectedin should be used with caution in patients with liver impairment or a history of heart conditions, and patients should be aware of the potential side effects of the medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LURBINECTEDIN
[2] https://reference.medscape.com/drug/zepzelca-lurbinectedin-4000075
[3] https://www.mayoclinic.org/drugs-supplements/lurbinectedin-intravenous-route/side-effects/drg-20490804?p=1



Follow-up:   How does lurbinectedin affect other medications? Can lurbinectedin be used with chemotherapy? Are there any dietary restrictions with lurbinectedin?





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